Glycophorin-A (GYPA) Antibody (Biotin)

Glycophorin-A (GYPA) Antibody (Biotin) is a mouse monoclonal antibody against Glycophorin-A (GYPA). Glycophorins A (GYPA) and B (GYPB) are major sialoglycoproteins of the human erythrocyte membrane which bear the antigenic determinants for the MN and Ss blood groups. In addition to the M or N and S or s antigens that commonly occur in all populations, about 40 related variant phenotypes have been identified. These variants include all the variants of the Miltenberger complex and several isoforms of Sta, as well as Dantu, Sat, He, Mg, and deletion variants Ena, S-s-U- and Mk. Most of the variants are the result of gene recombinations between GYPA and GYPB.

Target	Glycophorin-A (GYPA)
Clonality	Monoclonal
Clone	U564
Reactivity	Human, Rat
Tested Applications	IHC, FCM
Host	Mouse
Recommended dilutions	FCM: 1-4 µg/ml. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Biotin
Immunogen	Membrane preparation from splenic hairy cell leukemia.
Isotype	IgG1
Purification	The purified antibody is conjugated with biotin-LC-NHS under optimum conditions. The reagent is free of unconjugated biotin.
Storage	Store at 2-8°C. Do not freeze.
UniProt Primary AC	P02724 (UniProt, ExPASy)
GeneID	2993
Buffer	PBS solution with 15 mM sodium azide.
Specificity	The mouse monoclonal antibody recognizes an epitope between amino acids 27 and 40 of the extracellular portion of CD235a (glycophorin A), a sialoglycoprotein expressed on early erythroblasts, late erythroblasts, erythroblasts, mature erythrocytes and the cells of erythroid cell lines K562 and HEL. The antibody does not react with glycophorin B.
Concentration	1 mg/ml
Availability	Shipped within 5-12 working days.
Note	This product is for research use only.

Research Articles on Glycophorin-A (GYPA)

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