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Guanine Nucleotide Binding Protein (G Protein), Alpha Activating Activity Polypeptide O (GNAO1) Antibody
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Catalogue No: abx001952
Price:
US$217.50
(Size: 20 µl)
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GNAO1 Antibody is a Rabbit Polyclonal antibody against GNAO1. Heterotrimeric G proteins are membrane bound GTPases that are linked to 7-TM receptors. Each G protein contains an alpha-, beta- and gamma-subunit and is bound to GDP in the 'off' state. Ligand-receptor binding results in detachment of the G protein, switching it to an 'on' state and permitting Galpha activation of second messenger signalling cascades. There are several types of Galpha proteins; Galphas and Galphai bind directly to adenylyl cyclase and stimulate or inhibit its activity, leading to an increase or decrease in cAMP levels respectively.
Research Articles on Guanine Nucleotide Binding Protein (G Protein), Alpha Activating Activity Polypeptide O (GNAO1)
| Target | Guanine Nucleotide Binding Protein (G Protein), Alpha Activating Activity Polypeptide O (GNAO1) |
| Clonality | Polyclonal |
| Reactivity | Human, Mouse, Rat |
| Tested Applications | ELISA, WB, IF/ICC |
| Host | Rabbit |
| Recommended dilutions | ELISA: 1 µg/ml, WB: 1/500 - 1/2000, IF/ICC: 1/50 - 1/200. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Recombinant protein corresponding to GNAO1. The exact sequence is proprietary. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified by affinity chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | P09471 (UniProt, ExPASy) |
| UniProt Secondary AC | P29777, Q8TD72, Q9UMV4 |
| UniProt Entry Name | GNAO_HUMAN |
| Gene Symbol | GNAO1 |
| GeneID | 2775 |
| NCBI Accession | NP_066268.1 |
| KEGG | hsa:2775 |
| String | 9606.ENSP00000262494 |
| Molecular Weight | Calculated MW: 40 kDa Observed MW: 39 kDa |
| Buffer | PBS, pH 7.3, containing 0.09% sodium azide, 50% glycerol. |
| Concentration | > 0.2 mg/ml |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |