G Protein Coupled Estrogen Receptor 1 (GPER1) Antibody

This gene is a member of the G-protein coupled receptor 1 family and encodes a multi-pass membrane protein that localizes to the endoplasmic reticulum. The protein binds estrogen, resulting in intracellular calcium mobilization and synthesis of phosphatidylinositol 3, 4, 5-trisphosphate in the nucleus. This protein therefore plays a role in the rapid nongenomic signaling events widely observed following stimulation of cells and tissues with estrogen. Alternate transcriptional splice variants which encode the same protein have been characterized. [provided by RefSeq].

Target	G Protein Coupled Estrogen Receptor 1 (GPER1)
Clonality	Polyclonal
Reactivity	Human, Mouse, Rat
Tested Applications	ELISA, WB
Host	Rabbit
Recommended dilutions	WB: 1/1000 - 1/2000. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	KLH-conjugated synthetic peptide between 346-375 amino acids from the C-terminal region of human GPER.
Isotype	IgG
Form	Liquid
Purification	Purified through a protein A column, followed by peptide affinity purification.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	Q99527 (UniProt, ExPASy)
UniProt Entry Name	GPER1_HUMAN
Gene Symbol	GPER1
KEGG	hsa:2852
String	9606.ENSP00000380281
Molecular Weight	Calculated MW: 42.2 kDa
Buffer	PBS containing 0.09% sodium azide.
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on G Protein Coupled Estrogen Receptor 1 (GPER1)

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