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Transmembrane Glycoprotein NMB (GPNMB) Antibody
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Catalogue No: abx015876
Price:
US$420.50
(Size: 100 µl)
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The protein encoded by this gene is a type I transmembrane glycoprotein which shows homology to the pMEL17 precursor, a melanocyte-specific protein.GPNMB shows expression in the lowly metastatic human melanoma cell lines and xenografts but does not show expression in the highly metastatic cell lines.GPNMB may be involved in growth delay and reduction of metastatic potential.Two transcript variants encoding different isoforms have been found for this gene.
Research Articles on Transmembrane Glycoprotein NMB (GPNMB)
| Target | Transmembrane Glycoprotein NMB (GPNMB) |
| Clonality | Monoclonal |
| Reactivity | Human |
| Tested Applications | ELISA, WB, IHC |
| Host | Mouse |
| Recommended dilutions | ELISA: 1/10000, WB: 1/500 - 1/2000, IHC: 1/200 - 1/1000. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Purified recombinant fragment of human GPNMB (AA: 31-260) expressed in E. coli. |
| Isotype | IgG1 |
| Form | Liquid |
| Purification | Purified from ascites by Protein G chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | Q14956 (UniProt, ExPASy) |
| UniProt Secondary AC | A4D155, Q6UVX1, Q8N1A1 |
| Gene Symbol | GPNMB |
| GeneID | 10457 |
| OMIM | 604368 |
| HGNC | 4462 |
| Ensembl | ENSG00000136235 |
| Molecular Weight | 64 kDa |
| Buffer | PBS, containing 0.05% sodium azide. |
| Concentration | 1 mg/ml |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |