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Uracil Nucleotide/Cysteinyl Leukotriene Receptor (GPR17) Antibody
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Catalogue No: abx034541
Price:
US$326.25
(Size: 80 µl)
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Members of the G protein coupled receptor (GPCR) superfamily contain 7 transmembrane domains and transduce extracellular signals through heterotrimeric G proteins. The organization of the GPR17 gene differs from that of many other GPCRs in that the open reading frame is distributed on 2 exons; an additional exon contains the 5 prime untranslated region. Human GPR17 is expressed as 2.3 and 6.3 kb mRNAs exclusively in brain. The 2 transcripts appear to represent alternatively polyadenylated variants. Based on protein sequence homology and the conservation of certain key residues, GPR17 appears to be closely related to the P2Y family of GPCRs. There are two nemed isoforms.
Research Articles on Uracil Nucleotide/Cysteinyl Leukotriene Receptor (GPR17)
| Target | Uracil Nucleotide/Cysteinyl Leukotriene Receptor (GPR17) |
| Clonality | Polyclonal |
| Reactivity | Human |
| Tested Applications | ELISA, WB, IHC, FCM |
| Host | Rabbit |
| Recommended dilutions | WB: 1/1000, IHC-P: 1/50 - 1/100, FCM: 1/10 - 1/50. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | KLH-conjugated synthetic peptide between 230-258 amino acids from the Central region of human GPR17. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified through a protein A column, followed by peptide affinity purification. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | Q13304 (UniProt, ExPASy) |
| UniProt Secondary AC | A8K9L0, B2R9X0, Q8N5S7, Q9UDZ6, Q9UE21 |
| UniProt Entry Name | GPR17_HUMAN |
| KEGG | hsa:2840 |
| String | 9606.ENSP00000442982 |
| Molecular Weight | Calculated MW: 41 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |