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C5a Anaphylatoxin Chemotactic Receptor 2 (C5AR2) Antibody
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Catalogue No: abx031350
Price:
US$326.25
(Size: 80 µl)
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The anaphylatoxins C3a (see MIM 120700), C4a (see MIM 120810), and C5a are cationic fragments generated during the complement cascade that participate in host defense. In the case of inappropriate complement activation, anaphylatoxins may be involved in autoimmunity and sepsis. C5L2 is coexpressed with the C5a receptor, C5AR (C5R1; MIM 113995), on polymorphonuclear neutrophils and may modulate C5AR activity (Gerard et al., 2005 [PubMed 16204243]).
Research Articles on C5a Anaphylatoxin Chemotactic Receptor 2 (C5AR2)
| Target | C5a Anaphylatoxin Chemotactic Receptor 2 (C5AR2) |
| Clonality | Polyclonal |
| Reactivity | Human |
| Tested Applications | ELISA, WB |
| Host | Rabbit |
| Recommended dilutions | WB: 1/1000. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | KLH-conjugated synthetic peptide between 297-325 amino acids from the C-terminal region of human GPR77. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified through a protein A column, followed by peptide affinity purification. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | Q9P296 (UniProt, ExPASy) |
| UniProt Secondary AC | B2RA09 |
| UniProt Entry Name | C5AR2_HUMAN |
| Gene Symbol | C5AR2 |
| String | 9606.ENSP00000472620 |
| Molecular Weight | Calculated MW: 36.1 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |