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Growth Factor Receptor Bound Protein 2 (GRB2) Antibody
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Catalogue No: abx032777
Price:
US$326.25
(Size: 80 µl)
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GRB2 binds the epidermal growth factor receptor and contains one SH2 domain and two SH3 domains. Its two SH3 domains direct complex formation with proline-rich regions of other proteins, and its SH2 domain binds tyrosine phosphorylated sequences. This gene is similar to the Sem5 gene of C.elegans, which is involved in the signal transduction pathway.
Research Articles on Growth Factor Receptor Bound Protein 2 (GRB2)
| Target | Growth Factor Receptor Bound Protein 2 (GRB2) |
| Clonality | Polyclonal |
| Reactivity | Human |
| Tested Applications | ELISA, WB, IHC |
| Host | Rabbit |
| Recommended dilutions | WB: 1/1000, IHC-P: 1/10 - 1/50. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | KLH-conjugated synthetic peptide between 187-216 amino acids from human GRB2. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified through a protein A column, followed by peptide affinity purification. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | P62993 (UniProt, ExPASy) |
| UniProt Secondary AC | P29354, Q14450, Q63057, Q63059 |
| UniProt Entry Name | GRB2_HUMAN |
| KEGG | hsa:2885 |
| String | 9606.ENSP00000376345 |
| Molecular Weight | Calculated MW: 25.2 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Specificity | Predicted to react with Mouse, Rat and Xenopus GRB2. |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |