+44 (0) 1223 755950
+1 832 327 7413
Growth Factor Receptor Bound Protein 2 (GRB2) Antibody
REQUEST MORE INFO
Catalogue No: abx004351
Price:
US$217.50
(Size: 20 µl)
Reviews: 
(0 Publications and Reviews)
(0 Publications and Reviews)
Click on the image to see the image legend
GRB2 Antibody is a Rabbit Polyclonal antibody against GRB2. The protein encoded by this gene binds the epidermal growth factor receptor and contains one SH2 domain and two SH3 domains. Its two SH3 domains direct complex formation with proline-rich regions of other proteins, and its SH2 domain binds tyrosine phosphorylated sequences. This gene is similar to the Sem5 gene of C.elegans, which is involved in the signal transduction pathway. Two alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Research Articles on Growth Factor Receptor Bound Protein 2 (GRB2)
| Target | Growth Factor Receptor Bound Protein 2 (GRB2) |
| Clonality | Polyclonal |
| Reactivity | Human, Mouse |
| Tested Applications | ELISA, WB, IF/ICC |
| Host | Rabbit |
| Recommended dilutions | WB: 1/500-1/2000, IF/ICC: 1/10-1/100. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 1-217 of Human GRB2. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified by affinity chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | P62993 (UniProt, ExPASy) |
| UniProt Secondary AC | P29354, Q14450, Q63057, Q63059 |
| UniProt Entry Name | GRB2_HUMAN |
| Gene Symbol | GRB2 |
| GeneID | 2885 |
| NCBI Accession | NP_002077.1 |
| KEGG | hsa:2885 |
| String | 9606.ENSP00000376345 |
| Molecular Weight | Calculated MW: 25 kDa Observed MW: 33 kDa |
| Buffer | PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol. |
| Concentration | 0.52 mg/ml |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |