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Glutamate Receptor, Ionotropic, AMPA 3 (GRIA3) Antibody
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Catalogue No: abx010850
Price:
US$427.75
(Size: 100 µl)
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Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. These receptors are heteromeric protein complexes composed of multiple subunits, arranged to form ligand-gated ion channels. The classification of glutamate receptors is based on their activation by different pharmacologic agonists. The subunit encoded by this gene belongs to a family of AMPA (alpha amino-3-hydroxy-5-methyl-4-isoxazole propionate)-sensitive glutamate receptors, and is subject to RNA editing (AGA->GGA; R->G). Alternative splicing at this locus results in different isoforms, which may vary in their signal transduction properties.
Research Articles on Glutamate Receptor, Ionotropic, AMPA 3 (GRIA3)
| Target | Glutamate Receptor, Ionotropic, AMPA 3 (GRIA3) |
| Clonality | Monoclonal |
| Reactivity | Human |
| Tested Applications | ELISA, IHC |
| Host | Mouse |
| Recommended dilutions | ELISA: 1/10000, IHC: 1/200 - 1/1000. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Purified recombinant fragment of human GRIA3 expressed in E. coli. |
| Isotype | IgG1 |
| Form | Liquid |
| Purification | Unpurified ascites. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | P42263 (UniProt, ExPASy) |
| UniProt Secondary AC | D3DTF1, Q4VXD5, Q4VXD6, Q9HDA0, Q9HDA1, Q9HDA2, Q9P0H1 |
| UniProt Entry Name | GRIA3_HUMAN |
| Gene Symbol | GRIA3 |
| GeneID | 2892 |
| OMIM | 300699 |
| HGNC | 4573 |
| KEGG | hsa:2892 |
| Ensembl | ENSG00000125675 |
| String | 9606.ENSP00000481554 |
| Molecular Weight | 101 kDa |
| Buffer | Ascitic fluid containing 0.03% sodium azide. |
| Concentration | Not determined. |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |