+44 (0) 1223 755950
+1 832 327 7413
orders@abbexa.com
Help us improve!
How easy was it for you
to use the website?
to use the website?
How can we improve?
Submit
Sales & Advice:
UK +44 (0) 1223 755950 US +1 832 327 7413 @
Glutamate Receptor, Ionotropic, AMPA 1 (GRIA4) Antibody
REQUEST MORE INFO
Catalogue No: abx027106
Price:
US$326.25
(Size: 80 µl)
Orders to United States ship from United States
Click on the image to see the image legend
Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. These receptors are heteromeric protein complexes composed of multiple subunits, arranged to form ligand-gated ion channels. The classification of glutamate receptors is based on their activation by different pharmacologic agonists. The subunit encoded by this gene belongs to a family of AMPA (alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate) sensitive glutamate receptors, and is subject to RNA editing (AGA->GGA; R->G). Alternative splicing of this gene results in transcript variants encoding different isoforms, which may vary in their signal transduction properties. Some haplotypes of this gene show a positive association with schizophrenia. [provided by RefSeq].
Research Articles on Glutamate Receptor, Ionotropic, AMPA 1 (GRIA4)
| Target | Glutamate Receptor, Ionotropic, AMPA 1 (GRIA4) |
| Clonality | Polyclonal |
| Reactivity | Human, Mouse |
| Tested Applications | ELISA, WB, IHC |
| Host | Rabbit |
| Recommended dilutions | WB: 1/1000, IHC-P: 1/10 - 1/50. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | KLH-conjugated synthetic peptide between 296-325 amino acids from the Central region of human GRIA4. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified through a protein A column, followed by peptide affinity purification. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | P48058 (UniProt, ExPASy) |
| UniProt Secondary AC | Q86XE8 |
| UniProt Entry Name | GRIA4_HUMAN |
| KEGG | hsa:2893 |
| String | 9606.ENSP00000282499 |
| Molecular Weight | Calculated MW: 101 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Specificity | Predicted to react with Rat and Monkey GRIA4. |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
