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Glutamate Receptor Ionotropic, Kainate 2 (GRIK2) Antibody
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Catalogue No: abx028048
Price:
US$326.25
(Size: 80 µl)
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Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. This gene product belongs to the kainate family of glutamate receptors, which are composed of four subunits and function as ligand-activated ion channels. The subunit encoded by this gene is subject to RNA editing at multiple sites within the first and second transmembrane domains, which is thought to alter the structure and function of the receptor complex. Alternatively spliced transcript variants encoding different isoforms have also been described for this gene. Mutations in this gene have been associated with autosomal recessive mental retardation.
Research Articles on Glutamate Receptor Ionotropic, Kainate 2 (GRIK2)
| Target | Glutamate Receptor Ionotropic, Kainate 2 (GRIK2) |
| Clonality | Polyclonal |
| Reactivity | Human |
| Tested Applications | ELISA, WB |
| Host | Rabbit |
| Recommended dilutions | WB: 1/1000. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | KLH-conjugated synthetic peptide between 828-856 amino acids from the C-terminal region of human GRIK2. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified through a protein A column, followed by peptide affinity purification. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | Q13002 (UniProt, ExPASy) |
| UniProt Entry Name | GRIK2_HUMAN |
| KEGG | hsa:2898 |
| String | 9606.ENSP00000397026 |
| Molecular Weight | Calculated MW: 103 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Specificity | Predicted to react with Mouse, Rat, Monkey and Xenopus GRIK2. |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |