+44 (0) 1223 755950
+1 832 327 7413
Glutamate Receptor Ionotropic, NMDA 2B Phospho-Tyr1474 (GRIN2B pY1474) Antibody
REQUEST MORE INFO
Catalogue No: abx000405
Price:
US$232.00
(Size: 20 µl)
Reviews: 
(0 Publications and Reviews)
(0 Publications and Reviews)
Click on the image to see the image legend
GRIN2B (pY1474) Antibody is a Rabbit Polyclonal antibody against GRIN2B (pY1474). NMDA (NMDA) Receptors are a class of Ionotropic glutamate Receptors. NMDA Receptor channel has been shown to be involved in long-term potentiation, an activity-dependent increase in the efficiency of synaptic transmission thought to underlie certain kinds of memory and learning. NMDA Receptor channels are heteromers composed of three different subunits: NR1 (GRIN1), NR2 (GRIN2A, GRIN2B, GRIN2C, or GRIN2D) and NR3 (GRIN3A or GRIN3B). The NR2 subunit acts as the agonist binding site for glutamate. This Receptor is the predominant excitatory neurotransmitter Receptor in the mammalian brain.
Research Articles on GRIN2B (pY1474)
| Target | GRIN2B (pY1474) |
| Clonality | Polyclonal |
| Reactivity | Human |
| Tested Applications | WB |
| Host | Rabbit |
| Recommended dilutions | WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | A synthetic phosphorylated peptide around Y1474 of human GRIN2B. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified by affinity chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | Q13224 (UniProt, ExPASy) |
| UniProt Secondary AC | Q12919, Q13220, Q13225, Q14CU4, Q9UM56 |
| UniProt Entry Name | NMDE2_HUMAN |
| Gene Symbol | GRIN2B |
| GeneID | 2904 |
| NCBI Accession | NP_000825.2 |
| KEGG | hsa:2904 |
| String | 9606.ENSP00000477455 |
| Molecular Weight | Calculated MW: 166 kDa Observed MW: 200 kDa |
| Buffer | PBS, pH 7.3, containing 0.01% thimerosal, 50% glycerol. |
| Concentration | > 0.2 mg/ml |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |