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Growth Arrest And DNA Damage-Inducible, Alpha (GADD45A) Antibody
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Catalogue No: abx001489
Price:
US$348.00
(Size: 60 µl)
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GADD45A Antibody is a Rabbit Polyclonal antibody against GADD45A. This gene is a member of a group of genes whose transcript levels are increased following stressful growth arrest conditions and treatment with DNA-damaging agents. The protein encoded by this gene responds to environmental stresses by mediating activation of the p38/JNK pathway via MTK1/MEKK4 kinase. The DNA damage-induced transcription of this gene is mediated by both p53-dependent and -independent mechanisms. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.
Research Articles on Growth Arrest And DNA Damage-Inducible, Alpha (GADD45A)
| Target | Growth Arrest And DNA Damage-Inducible, Alpha (GADD45A) |
| Clonality | Polyclonal |
| Reactivity | Human, Mouse, Rat |
| Tested Applications | WB, IHC |
| Host | Rabbit |
| Recommended dilutions | WB: 1/500 - 1/2000, IHC-P: 1/50 - 1/200. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | A synthetic peptide corresponding to human GADD45A |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified by affinity chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | P24522 (UniProt, ExPASy) |
| UniProt Secondary AC | Q5TCA7, Q5TCA8 |
| UniProt Entry Name | GA45A_HUMAN |
| GeneID | 1647 |
| NCBI Accession | NP_001915.1 |
| KEGG | hsa:1647 |
| String | 9606.ENSP00000360025 |
| Molecular Weight | Calculated MW: 14 kDa/18 kDa Observed MW: 18 kDa |
| Buffer | PBS, pH 7.3, containing 0.01% thiomersal, 50% glycerol. |
| Concentration | 1 mg/ml |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |