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Growth Factor Receptor Bound Protein 2 (GRB2) Antibody
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Catalogue No: abx146629
Price:
US$406.00
(Size: 100 µg)
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Growth Factor Receptor Bound Protein 2 (GRB2) Antibody is a Rabbit Polyclonal antibody for the detection of GRB2. The protein encoded by this gene binds the epidermal growth factor receptor and contains one SH2 domain and two SH3 domains. Its two SH3 domains direct complex formation with proline-rich regions of other proteins, and its SH2 domain binds tyrosine phosphorylated sequences. This gene is similar to the Sem5 gene of C.elegans, which is involved in the signal transduction pathway. Two alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Research Articles on Growth Factor Receptor Bound Protein 2 (GRB2)
| Target | Growth Factor Receptor Bound Protein 2 (GRB2) |
| Clonality | Polyclonal |
| Reactivity | Human, Mouse, Rat |
| Tested Applications | ELISA, WB, IHC |
| Host | Rabbit |
| Recommended dilutions | WB: 1/500 - 1/2000, IHC: 1/50 - 1/200. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | growth factor receptor-bound protein 2 |
| Isotype | IgG |
| Form | Liquid |
| Purity | ≥ 95% (SDS-PAGE) |
| Purification | Purified by immunogen affinity chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Validity | 12 months. |
| UniProt Primary AC | P62993 (UniProt, ExPASy) |
| UniProt Secondary AC | P29354, Q14450, Q63057, Q63059 |
| UniProt Entry Name | GRB2_HUMAN |
| Gene Symbol | GRB2 |
| GeneID | 2885 |
| OMIM | 108355 |
| HGNC | 4566 |
| KEGG | hsa:2885 |
| Ensembl | ENSG00000177885 |
| String | 9606.ENSP00000376345 |
| Molecular Weight | Observed MW: 25 kDa |
| Buffer | PBS, pH 7.3, with 0.02% sodium azide and 50% glycerol. |
| Concentration | 2 mg/ml |
| Availability | Shipped within 5-12 working days. |
| Note | This product is for research use only. |