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Glycogen Synthase Kinase 3 Beta (GSK3B) Antibody
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Catalogue No: abx001694
Price:
US$217.50
(Size: 20 µl)
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GSK3B Antibody is a Rabbit Polyclonal antibody against GSK3B. The protein encoded by this gene is a serine-threonine kinase, belonging to the glycogen synthase kinase subfamily. It is involved in energy metabolism, neuronal cell development, and body pattern formation. Polymorphisms in this gene have been implicated in modifying risk of Parkinson disease, and studies in mice show that overexpression of this gene may be relevant to the pathogenesis of Alzheimer disease. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Research Articles on Glycogen Synthase Kinase 3 Beta (GSK3B)
| Target | Glycogen Synthase Kinase 3 Beta (GSK3B) |
| Clonality | Polyclonal |
| Reactivity | Human, Mouse, Rat |
| Tested Applications | ELISA, WB, IHC, IF/ICC, IP |
| Host | Rabbit |
| Recommended dilutions | ELISA: 1 µg/ml, WB: 1/500 - 1/2000, IHC-P: 1/50 - 1/200, IF/ICC: 1/50 - 1/200, IP: 0.5 µg - 4 µg antibody per 200 µg - 400 µg extracts of whole cells. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | A synthetic peptide corresponding to a sequence within amino acids 350-420 of human GSK3β. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified by affinity chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | P49841 (UniProt, ExPASy) |
| UniProt Secondary AC | D3DN89, Q9BWH3, Q9UL47 |
| UniProt Entry Name | GSK3B_HUMAN |
| Gene Symbol | GSK3B |
| GeneID | 2932 |
| NCBI Accession | NP_001139628.1 |
| KEGG | hsa:2932 |
| String | 9606.ENSP00000324806 |
| Molecular Weight | Calculated MW: 47 kDa Observed MW: 46 kDa |
| Buffer | PBS, pH 7.3, containing 0.09% Sodium azide, 50% glycerol. |
| Concentration | > 0.2 mg/ml |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |