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GTP Binding Protein 4 (GTPBP4) Antibody
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Catalogue No: abx003428
Price:
US$203.00
(Size: 20 µl)
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GTPBP4 Antibody is a Rabbit Polyclonal antibody against GTPBP4. GTP-binding proteins are GTPases and function as molecular switches that can flip between two states: active, when GTP is bound, and inactive, when GDP is bound. 'Active' in this context usually means that the molecule acts as a signal to trigger other events in the cell. When an extracellular ligand binds to a G-protein-linked receptor, the receptor changes its conformation and switches on the trimeric G proteins that associate with it by causing them to eject their GDP and replace it with GTP. The switch is turned off when the G protein hydrolyzes its own bound GTP, converting it back to GDP. But before that occurs, the active protein has an opportunity to diffuse away from the receptor and deliver its message for a prolonged period to its downstream target.
Research Articles on GTP Binding Protein 4 (GTPBP4)
| Target | GTP Binding Protein 4 (GTPBP4) |
| Clonality | Polyclonal |
| Reactivity | Human, Mouse, Rat |
| Tested Applications | WB, IHC, IF/ICC |
| Host | Rabbit |
| Recommended dilutions | WB: 1/1000 - 1/2000, IHC-P: 1/50 - 1/200, IF/ICC: 1/50 - 1/200. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 385-634 of human GTPBP4. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified by affinity chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | Q9BZE4 (UniProt, ExPASy) |
| UniProt Secondary AC | B3KMC5, B4DY13, B7Z7A3, O95446, Q5T3R8, Q9NVJ8 |
| UniProt Entry Name | NOG1_HUMAN |
| Gene Symbol | GTPBP4 |
| GeneID | 23560 |
| NCBI Accession | NP_036473.2 |
| String | 9606.ENSP00000354040 |
| Molecular Weight | Calculated MW: 74 kDa Observed MW: 74 kDa |
| Buffer | PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol. |
| Concentration | > 0.2 mg/ml |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |