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Retinal Guanylyl Cyclase 1 (GUCY2D) Antibody
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Catalogue No: abx002605
Price:
US$203.00
(Size: 20 µl)
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GUCY2D Antibody is a Rabbit Polyclonal antibody against GUCY2D. This gene encodes a retina-specific guanylate cyclase, which is a member of the membrane guanylyl cyclase family. Like other membrane guanylyl cyclases, this enzyme has a hydrophobic amino-terminal signal sequence followed by a large extracellular domain, a single membrane spanning domain, a kinase homology domain, and a guanylyl cyclase catalytic domain. In contrast to other membrane guanylyl cyclases, this enzyme is not activated by natriuretic peptides. Mutations in this gene result in Leber congenital amaurosis and cone-rod dystrophy-6 diseases.
Research Articles on Retinal Guanylyl Cyclase 1 (GUCY2D)
| Target | Retinal Guanylyl Cyclase 1 (GUCY2D) |
| Clonality | Polyclonal |
| Reactivity | Human, Mouse, Rat |
| Tested Applications | WB |
| Host | Rabbit |
| Recommended dilutions | WB: 1/200 - 1/2000. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 52-350 of human GUCY2D. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified by affinity chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | Q02846 (UniProt, ExPASy) |
| UniProt Secondary AC | Q6LEA7 |
| UniProt Entry Name | GUC2D_HUMAN |
| Gene Symbol | GUCY2D |
| GeneID | 3000 |
| NCBI Accession | NP_000171.1 |
| KEGG | hsa:3000 |
| String | 9606.ENSP00000254854 |
| Molecular Weight | Calculated MW: 120 kDa Observed MW: 95 kDa |
| Buffer | PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol. |
| Concentration | > 0.2 mg/ml |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |