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Granzyme B (GZMB) Antibody
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Catalogue No: abx001994
Price:
US$203.00
(Size: 20 µl)
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GZMB Antibody is a Rabbit Polyclonal antibody against GZMB. Cytolytic T lymphocytes (CTL) and natural killer (NK) cells share the remarkable ability to recognize, bind, and lyse specific target cells. They are thought to protect their host by lysing cells bearing on their surface 'nonself' antigens, usually peptides or proteins resulting from infection by intracellular pathogens. The protein encoded by this gene is crucial for the rapid induction of target cell apoptosis by CTL in cell-mediated immune response.
Research Articles on Granzyme B (GZMB)
| Target | Granzyme B (GZMB) |
| Clonality | Polyclonal |
| Reactivity | Human, Mouse, Rat |
| Tested Applications | WB, IHC, IF/ICC |
| Host | Rabbit |
| Recommended dilutions | WB: 1/500 - 1/1000, IHC-P: 1/50 - 1/200, IF/ICC: 1/50 - 1/200. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | A synthetic peptide corresponding to a sequence within amino acids 100-200 of human Granzyme B. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified by affinity chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | P10144 (UniProt, ExPASy) |
| UniProt Secondary AC | Q8N1D2, Q9UCC1 |
| UniProt Entry Name | GRAB_HUMAN |
| Gene Symbol | GZMB |
| GeneID | 3002 |
| OMIM | 123910 |
| NCBI Accession | NP_004122.2 |
| HGNC | 4709 |
| KEGG | hsa:3002 |
| Ensembl | ENSG00000100453 |
| String | 9606.ENSP00000216341 |
| Molecular Weight | Calculated MW: 28 kDa Observed MW: 30 kDa |
| Buffer | PBS, pH 7.3, containing 0.05% Proclin-300, 50% glycerol. |
| Concentration | 1.92 mg/ml |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |