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Histone H2A.X (H2AFX) Antibody
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Catalogue No: abx027558
Price:
US$326.25
(Size: 80 µl)
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Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene encodes a member of the histone H2A family, and generates two transcripts through the use of the conserved stem-loop termination motif, and the polyA addition motif.
Research Articles on Histone H2A.X (H2AFX)
| Target | Histone H2A.X (H2AFX) |
| Clonality | Polyclonal |
| Reactivity | Human |
| Tested Applications | ELISA, WB, IHC |
| Host | Rabbit |
| Recommended dilutions | WB: 1/1000, IHC-P: 1/10 - 1/50. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | KLH-conjugated synthetic peptide between 111-140 amino acids from the C-terminal region of human H2AFX. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified through a protein A column, followed by peptide affinity purification. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | P16104 (UniProt, ExPASy) |
| UniProt Secondary AC | Q4ZGJ7, Q6IAS5 |
| UniProt Entry Name | H2AX_HUMAN |
| KEGG | hsa:3014 |
| String | 9606.ENSP00000434024 |
| Molecular Weight | Calculated MW: 15.1 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |