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H2A Histone Family Member Y2 (H2AFY2) Antibody
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Catalogue No: abx025873
Price:
US$326.25
(Size: 80 µl)
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Variant histone H2A which replaces conventional H2A in a subset of nucleosomes where it represses transcription. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. May be involved in stable X chromosome inactivation.
Research Articles on H2A Histone Family Member Y2 (H2AFY2)
| Target | H2A Histone Family Member Y2 (H2AFY2) |
| Clonality | Polyclonal |
| Reactivity | Human, Mouse |
| Tested Applications | ELISA, WB, FCM |
| Host | Rabbit |
| Recommended dilutions | WB: 1/1000, FCM: 1/10 - 1/50. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | KLH-conjugated synthetic peptide between 11-39 amino acids from the N-terminal region of human H2AFY2. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified through a protein A column, followed by peptide affinity purification. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | Q9P0M6 (UniProt, ExPASy) |
| UniProt Secondary AC | Q5SQT2 |
| UniProt Entry Name | H2AW_HUMAN |
| Gene Symbol | H2AFY2 |
| String | 9606.ENSP00000362352 |
| Molecular Weight | Calculated MW: 40.1 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |