H2A Histone Family Member Z (H2AFZ) Antibody

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Catalogue No: abx026163
Price: US$326.25
(Size: 80 µl)
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H2A Histone Family Member Z (H2AFZ) Antibody
H2A Histone Family Member Z (H2AFZ) Antibody H2A Histone Family Member Z (H2AFZ) Antibody

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Datasheet SDS
Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene encodes a replication-independent member of the histone H2A family that is distinct from other members of the family. Studies in mice have shown that this particular histone is required for embryonic development and indicate that lack of functional histone H2A leads to embryonic lethality. [provided by RefSeq].

Target H2A Histone Family Member Z (H2AFZ)
Clonality Polyclonal
Reactivity Human
Tested Applications ELISA, WB, IHC
Host Rabbit
Recommended dilutions WB: 1/1000, IHC-P: 1/10 - 1/50. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user.
Conjugation Unconjugated
Immunogen KLH-conjugated synthetic peptide between 59-86 amino acids from the C-terminal region of human H2AFZ.
Isotype IgG
Form Liquid
Purification Purified through a protein A column, followed by peptide affinity purification.
Storage Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC P0C0S5 (UniProt, ExPASy)
UniProt Secondary AC B2RD56, P17317, Q6I9U0
UniProt Entry Name H2AZ_HUMAN
KEGG hsa:3015
String 9606.ENSP00000296417
Molecular Weight Calculated MW: 13.6 kDa
Buffer PBS containing 0.09% sodium azide.
Specificity Predicted to react with Mouse, Rat, Cow, Sheep, Zebrafish, Drosophila, Xenopus and C. elegans H2AZ1.
Availability Shipped within 5-10 working days.
Note THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION.
Research Articles on H2A Histone Family Member Z (H2AFZ)
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