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H2A Histone Family Member Z (H2AFZ) Antibody
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Catalogue No: abx005072
Price:
US$232.00
(Size: 20 µl)
Orders to United States ship from United States
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![Western blot analysis of various lysates using [KO Validated] Histone H2A.Z Antibody at 1/1000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) at 1/10000 dilution. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Exposure time: 30s.](https://www.abbexa.com/image/cache/data/products/18B/abx005072_1-500x500.jpg "H2A Histone Family Member Z (H2AFZ) Antibody")
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H2AFZ Antibody is a Rabbit Polyclonal antibody against H2AFZ. Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene encodes a replication-independent member of the histone H2A family that is distinct from other members of the family. Studies in mice have shown that this particular histone is required for embryonic development and indicate that lack of functional histone H2A leads to embryonic lethality.
Research Articles on H2A Histone Family Member Z (H2AFZ)
| Target | H2A Histone Family Member Z (H2AFZ) |
| Clonality | Polyclonal |
| Reactivity | Human, Mouse, Rat |
| Tested Applications | ELISA, WB |
| Host | Rabbit |
| Recommended dilutions | ELISA: 1 µg/ml, WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 1-128 of human H2AFZ. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified by affinity chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | P0C0S5 (UniProt, ExPASy) |
| UniProt Secondary AC | B2RD56, P17317, Q6I9U0 |
| UniProt Entry Name | H2AZ_HUMAN |
| Gene Symbol | H2AZ1 |
| GeneID | 3015 |
| NCBI Accession | NP_002097.1 |
| KEGG | hsa:3015 |
| String | 9606.ENSP00000296417 |
| Molecular Weight | Calculated MW: 13 kDa Observed MW: 15 kDa |
| Buffer | PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol. |
| Concentration | > 0.2 mg/ml |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |