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Histone H2B Type W-T (H2BFWT) Antibody
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Catalogue No: abx028974
Price:
US$326.25
(Size: 80 µl)
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Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene encodes a member of the H2B histone family that is specifically expressed in sperm nuclei. A polymorphism in the 5' UTR of this gene is associated with male infertility.
Research Articles on Histone H2B Type W-T (H2BFWT)
| Target | Histone H2B Type W-T (H2BFWT) |
| Clonality | Polyclonal |
| Reactivity | Human |
| Tested Applications | ELISA, WB |
| Host | Rabbit |
| Recommended dilutions | WB: 1/1000. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | KLH-conjugated synthetic peptide between 62-88 amino acids from the Central region of human H2BFWT. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified through a protein A column, followed by peptide affinity purification. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | Q7Z2G1 (UniProt, ExPASy) |
| UniProt Secondary AC | B1AK72, Q147W3 |
| UniProt Entry Name | H2BWT_HUMAN |
| Gene Symbol | H2BFWT |
| KEGG | hsa:158983 |
| String | 9606.ENSP00000354723 |
| Molecular Weight | Calculated MW: 19.6 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |