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Trifunctional Enzyme Subunit Beta, Mitochondrial (HADHB) Antibody
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Catalogue No: abx034545
Price:
US$326.25
(Size: 80 µl)
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HADHB encodes the beta subunit of the mitochondrial trifunctional protein, which catalyzes the last three steps of mitochondrial beta-oxidation of long chain fatty acids. The mitochondrial membrane-bound heterocomplex is composed of four alpha and four beta subunits, with the beta subunit catalyzing the 3-ketoacyl-CoA thiolase activity. Mutations in this gene result in trifunctional protein deficiency. The encoded protein can also bind RNA and decreases the stability of some mRNAs. The genes of the alpha and beta subunits of the mitochondrial trifunctional protein are located adjacent to each other in the human genome in a head-to-head orientation.
Research Articles on Trifunctional Enzyme Subunit Beta, Mitochondrial (HADHB)
| Target | Trifunctional Enzyme Subunit Beta, Mitochondrial (HADHB) |
| Clonality | Polyclonal |
| Reactivity | Human |
| Tested Applications | ELISA, WB, FCM |
| Host | Rabbit |
| Recommended dilutions | WB: 1/1000, FCM: 1/10 - 1/50. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | KLH-conjugated synthetic peptide between 315-342 amino acids from the C-terminal region of human HADHB. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified through a protein A column, followed by peptide affinity purification. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | P55084 (UniProt, ExPASy) |
| UniProt Secondary AC | B2RB16, B4E2W0, O14969, Q53TA6, Q96C77, Q9H3F5, Q9T2V8 |
| UniProt Entry Name | ECHB_HUMAN |
| KEGG | hsa:3032 |
| String | 9606.ENSP00000325136 |
| Molecular Weight | Calculated MW: 51.3 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Specificity | Predicted to react with Cow and Monkey HADHB. |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |