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Trifunctional Enzyme Subunit Beta, Mitochondrial (HADHB) Antibody
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Catalogue No: abx004370
Price:
US$203.00
(Size: 20 µl)
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HADHB Antibody is a Rabbit Polyclonal antibody against HADHB. This gene encodes the beta subunit of the mitochondrial trifunctional protein, which catalyzes the last three steps of mitochondrial beta-oxidation of long chain fatty acids. The mitochondrial membrane-bound heterocomplex is composed of four alpha and four beta subunits, with the beta subunit catalyzing the 3-ketoacyl-CoA thiolase activity. The encoded protein can also bind RNA and decreases the stability of some mRNAs. The genes of the alpha and beta subunits of the mitochondrial trifunctional protein are located adjacent to each other in the human genome in a head-to-head orientation. Mutations in this gene result in trifunctional protein deficiency. Alternatively spliced transcript variants encoding different isoforms have been described.
Research Articles on Trifunctional Enzyme Subunit Beta, Mitochondrial (HADHB)
| Target | Trifunctional Enzyme Subunit Beta, Mitochondrial (HADHB) |
| Clonality | Polyclonal |
| Reactivity | Human, Mouse, Rat |
| Tested Applications | WB, IF/ICC |
| Host | Rabbit |
| Recommended dilutions | WB: 1/100 - 1/500, IF/ICC: 1/10 - 1/100. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 34-270 of human HADHB. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified by affinity chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | P55084 (UniProt, ExPASy) |
| UniProt Secondary AC | B2RB16, B4E2W0, O14969, Q53TA6, Q96C77, Q9H3F5, Q9T2V8 |
| UniProt Entry Name | ECHB_HUMAN |
| Gene Symbol | HADHB |
| GeneID | 3032 |
| NCBI Accession | NP_000174.1 |
| KEGG | hsa:3032 |
| String | 9606.ENSP00000325136 |
| Molecular Weight | Calculated MW: 51 kDa Observed MW: 51 kDa |
| Buffer | PBS, pH 7.3, containing 0.05% Proclin-300, 50% glycerol. |
| Concentration | > 0.2 mg/ml |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |