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Hyaluronan Synthase 2 (HAS2) Antibody
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Catalogue No: abx010958
Price:
US$427.75
(Size: 100 µl)
Orders to United States ship from United States
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Catalyzes the addition of GlcNAc or GlcUA monosaccharides to the nascent hyaluronan polymer. Therefore, it is essential to hyaluronan synthesis a major component of most extracellular matrices that has a structural role in tissues architectures and regulates cell adhesion, migration and differentiation. This is one of the isozymes catalyzing that reaction and it is particularly responsible for the synthesis of high molecular mass hyaluronan. Required for the transition of endocardial cushion cells into mesenchymal cells, a process crucial for heart development. May also play a role in vasculogenesis. High molecular mass hyaluronan also play a role in early contact inhibition a process which stops cell growth when cells come into contact with each other or the extracellular matrix.
Research Articles on Hyaluronan Synthase 2 (HAS2)
| Target | Hyaluronan Synthase 2 (HAS2) |
| Clonality | Monoclonal |
| Clone | H010 |
| Reactivity | Human |
| Tested Applications | ELISA, WB, IHC, IF/ICC |
| Host | Mouse |
| Recommended dilutions | ELISA: 1/10000, WB: 1/500 - 1/2000, IHC: 1/200 - 1/1000, IF/ICC: 1/100 - 1/500. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Purified recombinant fragment corresponding to Human HAS2 (67-170 AA) expressed in E. coli. |
| Isotype | IgG1 |
| Form | Liquid |
| Purification | Purified from ascites by Protein G chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | Q92819 (UniProt, ExPASy) |
| UniProt Secondary AC | Q32MM3 |
| UniProt Entry Name | HYAS2_HUMAN |
| Gene Symbol | HAS2 |
| GeneID | 3037 |
| OMIM | 601636 |
| HGNC | 4819 |
| KEGG | hsa:3037 |
| Ensembl | ENSG00000170961 |
| String | 9606.ENSP00000306991 |
| Molecular Weight | 63.5 kDa |
| Buffer | PBS, containing 0.05% sodium azide. |
| Concentration | 1 mg/ml |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |