Hepatitis A Virus Cellular Receptor 2 (HAVCR2) Antibody

CD4 (MIM 186940) positive T helper lymphocytes can be divided into types 1 (Th1) and 2 (Th2) on the basis of their cytokine secretion patterns. Th1 cells and their associated cytokines are involved in cell-mediated immunity to intracellular pathogens and delayed-type hypersensitivity reactions, whereas Th2 cells are involved in the control of extracellular helminthic infections and the promotion of atopic and allergic diseases. The 2 types of cells also cross-regulate the functions of the other. TIM3 is a Th1-specific cell surface protein that regulates macrophage activation and enhances the severity of experimental autoimmune encephalomyelitis in mice.

Target	Hepatitis A Virus Cellular Receptor 2 (HAVCR2)
Clonality	Polyclonal
Reactivity	Human
Tested Applications	ELISA, WB
Host	Rabbit
Recommended dilutions	WB: 1/1000. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	KLH-conjugated synthetic peptide between 167-194 amino acids from the Central region of human HAVCR2.
Isotype	IgG
Form	Liquid
Purification	Purified through a protein A column, followed by peptide affinity purification.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	Q8TDQ0 (UniProt, ExPASy)
UniProt Secondary AC	B2RAY2, Q8WW60, Q96K94
UniProt Entry Name	HAVR2_HUMAN
Gene Symbol	HAVCR2
KEGG	hsa:84868
String	9606.ENSP00000312002
Molecular Weight	Calculated MW: 33.4 kDa
Buffer	PBS containing 0.09% sodium azide.
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Hepatitis A Virus Cellular Receptor 2 (HAVCR2)

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