Hemoglobin subunit alpha 2 Antibody

HBA2 located on chromosome 16 spans about 30 kb and includes seven loci: 5' zeta pseudozeta mu pseudoalpha-1 alpha-2 alpha-1 theta 3'. The alpha-2 (HBA2) and alpha-1 (HBA1) coding sequences are identical. These genes differ slightly over the 5' untranslated regions and the introns, but they differ significantly over the 3' untranslated regions. Two alpha chains plus two beta chains constitute HbA, which in normal adult life comprises about 97% of the total hemoglobin; alpha chains combine with delta chains to constitute HbA-2, which with HbF (fetal hemoglobin) makes up the remaining 3% of adult hemoglobin. Alpha thalassemias result from deletions of each of the alpha genes as well as deletions of both HBA2 and HBA1; some nondeletion alpha thalassemias have also been reported.

Target	Hemoglobin subunit alpha 2
Clonality	Polyclonal
Reactivity	Human, Mouse
Tested Applications	ELISA, WB, FCM
Host	Rabbit
Recommended dilutions	WB: 1/1000, FCM: 1/25. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	KLH-conjugated synthetic peptide between 100-128 amino acids from the Central region of human HBA2.
Isotype	IgG
Form	Liquid
Purification	Purified through a protein A column, followed by peptide affinity purification.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	P69905 (UniProt, ExPASy)
UniProt Secondary AC	P01922, Q1HDT5, Q3MIF5, Q53F97, Q96KF1, Q9NYR7, Q9UCM0
UniProt Entry Name	HBA_HUMAN
NCBI Accession	NP_000508.1 NP_000549.1
KEGG	hsa:3039 hsa:3040
String	9606.ENSP00000322421
Molecular Weight	Calculated MW: 15.3 kDa
Buffer	PBS containing 0.09% sodium azide.
Specificity	Predicted to react with Monkey HBA1.
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Hemoglobin subunit alpha 2

Write a review

Your Name

Your Email Address

PMID

DOI

Your Review

Rating

Continue