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Hemoglobin subunit alpha 2 Antibody
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Catalogue No: abx034365
Price:
US$326.25
(Size: 50 µl)
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HBA2 located on chromosome 16 spans about 30 kb and includes seven loci: 5' zeta pseudozeta mu pseudoalpha-1 alpha-2 alpha-1 theta 3'. The alpha-2 (HBA2) and alpha-1 (HBA1) coding sequences are identical. These genes differ slightly over the 5' untranslated regions and the introns, but they differ significantly over the 3' untranslated regions. Two alpha chains plus two beta chains constitute HbA, which in normal adult life comprises about 97% of the total hemoglobin; alpha chains combine with delta chains to constitute HbA-2, which with HbF (fetal hemoglobin) makes up the remaining 3% of adult hemoglobin. Alpha thalassemias result from deletions of each of the alpha genes as well as deletions of both HBA2 and HBA1; some nondeletion alpha thalassemias have also been reported.
Research Articles on Hemoglobin subunit alpha 2
| Target | Hemoglobin subunit alpha 2 |
| Clonality | Polyclonal |
| Reactivity | Human, Mouse |
| Tested Applications | ELISA, WB, FCM |
| Host | Rabbit |
| Recommended dilutions | WB: 1/1000, FCM: 1/25. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | KLH-conjugated synthetic peptide between 100-128 amino acids from the Central region of human HBA2. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified through a protein A column, followed by peptide affinity purification. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | P69905 (UniProt, ExPASy) |
| UniProt Secondary AC | P01922, Q1HDT5, Q3MIF5, Q53F97, Q96KF1, Q9NYR7, Q9UCM0 |
| UniProt Entry Name | HBA_HUMAN |
| NCBI Accession | NP_000508.1 NP_000549.1 |
| KEGG | hsa:3039 hsa:3040 |
| String | 9606.ENSP00000322421 |
| Molecular Weight | Calculated MW: 15.3 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Specificity | Predicted to react with Monkey HBA1. |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |