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Hemoglobin Subunit Gamma-1 (HBG1) Antibody
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Catalogue No: abx027543
Price:
US$326.25
(Size: 80 µl)
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The gamma globin genes (HBG1 and HBG2) are normally expressed in the fetal liver, spleen and bone marrow. Two gamma chains together with two alpha chains constitute fetal hemoglobin (HbF) which is normally replaced by adult hemoglobin (HbA) at birth. In some beta-thalassemias and related conditions, gamma chain production continues into adulthood. The two types of gamma chains differ at residue 136 where glycine is found in the G-gamma product (HBG2) and alanine is found in the A-gamma product (HBG1). The former is predominant at birth. The order of the genes in the beta-globin cluster is: 5'-epsilon gamma-G gamma-A delta beta--3'.
Research Articles on Hemoglobin Subunit Gamma-1 (HBG1)
| Target | Hemoglobin Subunit Gamma-1 (HBG1) |
| Clonality | Polyclonal |
| Reactivity | Human |
| Tested Applications | ELISA, WB |
| Host | Rabbit |
| Recommended dilutions | WB: 1/1000. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | KLH-conjugated synthetic peptide between 56-85 amino acids from the Central region of human HBG1. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified through a protein A column, followed by peptide affinity purification. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | P69891 (UniProt, ExPASy) |
| UniProt Secondary AC | P02096, P62027, Q549G1, Q8TDA1, Q96FH7 |
| UniProt Entry Name | HBG1_HUMAN |
| KEGG | hsa:3047 |
| Molecular Weight | Calculated MW: 16.1 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |