HBS1-Like Protein (HBS1L) Antibody

This gene encodes a member of the GTP-binding elongation factor family. It is expressed in multiple tissues with the highest expression in heart and skeletal muscle. The intergenic region of this gene and the MYB gene has been identified to be a quantitative trait locus (QTL) controlling fetal hemoglobin level, and this region influnces erythrocyte, platelet, and monocyte counts as well as erythrocyte volume and hemoglobin content. DNA polymorphisms at this region associate with fetal hemoglobin levels and pain crises in sickle cell disease. A single nucleotide polymorphism in exon 1 of this gene is significantly associated with severity in beta-thalassemia/Hemoglobin E. Multiple alternatively spliced transcript variants encoding different protein isoforms have been found for this gene.

Target	HBS1-Like Protein (HBS1L)
Clonality	Polyclonal
Reactivity	Human, Mouse
Tested Applications	ELISA, WB
Host	Rabbit
Recommended dilutions	WB: 1/1000. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	KLH-conjugated synthetic peptide between 460-486 amino acids from the Central region of human HBS1L.
Isotype	IgG
Form	Liquid
Purification	Purified through a protein A column, followed by peptide affinity purification.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	Q9Y450 (UniProt, ExPASy)
UniProt Secondary AC	B7Z365, Q4VX89, Q4VX90, Q5T7G3, Q8NDW9, Q9UPW3
UniProt Entry Name	HBS1L_HUMAN
Gene Symbol	HBS1L
GeneID	10767
OMIM	612450
HGNC	4834
KEGG	hsa:10767
Ensembl	ENSG00000112339
String	9606.ENSP00000356811
Molecular Weight	Calculated MW: 75.5 kDa
Buffer	PBS containing 0.09% sodium azide.
Specificity	Predicted to react with Rat and Cow HBS1L.
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on HBS1-Like Protein (HBS1L)

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