HCLS1-Associated Protein X-1 (HAX1) Antibody

HCLS1-Associated Protein X-1 (HAX1) Antibody is a Rabbit Polyclonal antibody for the detection of HAX1.

The protein encoded by this gene is known to associate with hematopoietic cell-specific Lyn substrate 1, a substrate of Src family tyrosine kinases. It also interacts with the product of the polycystic kidney disease 2 gene, mutations in which are associated with autosomal-dominant polycystic kidney disease, and with the F-actin-binding protein, cortactin. It was earlier thought that this gene product is mainly localized in the mitochondria, however, recent studies indicate it to be localized in the cell body. Mutations in this gene result in autosomal recessive severe congenital neutropenia, also known as Kostmann disease. Two transcript variants encoding different isoforms have been found for this gene.

Target	HCLS1-Associated Protein X-1 (HAX1)
Clonality	Polyclonal
Reactivity	Human, Mouse, Rat
Tested Applications	ELISA, WB
Host	Rabbit
Recommended dilutions	WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	HCLS1 associated protein X-1
Isotype	IgG
Form	Liquid
Purity	≥ 95% (SDS-PAGE)
Purification	Purified by immunogen affinity chromatography.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
Validity	12 months.
UniProt Primary AC	O00165 (UniProt, ExPASy)
UniProt Secondary AC	A8W4W9, A8W4X0, B4DUJ7, Q5VYD5, Q5VYD7, Q96AU4, Q9BS80
UniProt Entry Name	HAX1_HUMAN
Gene Symbol	HAX1
GeneID	10456
OMIM	605998
HGNC	16915
KEGG	hsa:10456
Ensembl	ENSG00000143575
String	9606.ENSP00000329002
Molecular Weight	Observed MW: 31 kDa, 36 kDa
Buffer	PBS, pH 7.3, with 0.02% sodium azide and 50% glycerol.
Concentration	2 mg/ml
Availability	Shipped within 5-12 working days.
Note	This product is for research use only.

Research Articles on HCLS1-Associated Protein X-1 (HAX1)

Write a review

Your Name

Your Email Address

PMID

DOI

Your Review

Rating

Continue