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HCLS1-Associated Protein X-1 (HAX1) Antibody
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Catalogue No: abx218459
Price:
US$406.00
(Size: 100 µg)
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HCLS1-Associated Protein X-1 (HAX1) Antibody is a Rabbit Polyclonal antibody for the detection of HAX1. The protein encoded by this gene is known to associate with hematopoietic cell-specific Lyn substrate 1, a substrate of Src family tyrosine kinases. It also interacts with the product of the polycystic kidney disease 2 gene, mutations in which are associated with autosomal-dominant polycystic kidney disease, and with the F-actin-binding protein, cortactin. It was earlier thought that this gene product is mainly localized in the mitochondria, however, recent studies indicate it to be localized in the cell body. Mutations in this gene result in autosomal recessive severe congenital neutropenia, also known as Kostmann disease. Two transcript variants encoding different isoforms have been found for this gene.
Research Articles on HCLS1-Associated Protein X-1 (HAX1)
| Target | HCLS1-Associated Protein X-1 (HAX1) |
| Clonality | Polyclonal |
| Reactivity | Human, Mouse, Rat |
| Tested Applications | ELISA, WB |
| Host | Rabbit |
| Recommended dilutions | WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | HCLS1 associated protein X-1 |
| Isotype | IgG |
| Form | Liquid |
| Purity | ≥ 95% (SDS-PAGE) |
| Purification | Purified by immunogen affinity chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Validity | 12 months. |
| UniProt Primary AC | O00165 (UniProt, ExPASy) |
| UniProt Secondary AC | A8W4W9, A8W4X0, B4DUJ7, Q5VYD5, Q5VYD7, Q96AU4, Q9BS80 |
| UniProt Entry Name | HAX1_HUMAN |
| Gene Symbol | HAX1 |
| GeneID | 10456 |
| OMIM | 605998 |
| HGNC | 16915 |
| KEGG | hsa:10456 |
| Ensembl | ENSG00000143575 |
| String | 9606.ENSP00000329002 |
| Molecular Weight | Observed MW: 31 kDa, 36 kDa |
| Buffer | PBS, pH 7.3, with 0.02% sodium azide and 50% glycerol. |
| Concentration | 2 mg/ml |
| Availability | Shipped within 5-12 working days. |
| Note | This product is for research use only. |