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Histone Deacetylase 4 (HDAC4) Antibody
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Catalogue No: abx027557
Price:
US$326.25
(Size: 80 µl)
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Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to class II of the histone deacetylase/acuc/apha family. It possesses histone deacetylase activity and represses transcription when tethered to a promoter. This protein does not bind DNA directly, but through transcription factors MEF2C and MEF2D. It seems to interact in a multiprotein complex with RbAp48 and HDAC3.
Research Articles on Histone Deacetylase 4 (HDAC4)
| Target | Histone Deacetylase 4 (HDAC4) |
| Clonality | Polyclonal |
| Reactivity | Human |
| Tested Applications | ELISA, WB, IHC, IF/ICC |
| Host | Rabbit |
| Recommended dilutions | WB: 1/1000, IHC-P: 1/10 - 1/50, IF/ICC: 1/10 - 1/50. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | KLH-conjugated synthetic peptide between 1049-1077 amino acids from the C-terminal region of human HDAC4. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified through a protein A column, followed by peptide affinity purification. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | P56524 (UniProt, ExPASy) |
| UniProt Secondary AC | E9PGB9, F5GX36, Q86YH7, Q9UND6 |
| UniProt Entry Name | HDAC4_HUMAN |
| KEGG | hsa:9759 |
| String | 9606.ENSP00000264606 |
| Molecular Weight | Calculated MW: 119 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |