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Histone Deacetylase 4 (HDAC4) Antibody
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Catalogue No: abx000624
Price:
US$348.00
(Size: 60 µl)
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HDAC4 Antibody is a Rabbit Polyclonal antibody against HDAC4. Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to class II of the histone deacetylase/acuc/apha family. It possesses histone deacetylase activity and represses transcription when tethered to a promoter. This protein does not bind DNA directly, but through transcription factors MEF2C and MEF2D. It seems to interact in a multiprotein complex with RbAp48 and HDAC3.
Research Articles on Histone Deacetylase 4 (HDAC4)
| Target | Histone Deacetylase 4 (HDAC4) |
| Clonality | Polyclonal |
| Reactivity | Human, Mouse, Rat |
| Tested Applications | IHC |
| Host | Rabbit |
| Recommended dilutions | IHC-P: 1/50 - 1/100. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Recombinant fusion protein corresponding to human HDAC4 |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified by affinity chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | P56524 (UniProt, ExPASy) |
| UniProt Secondary AC | E9PGB9, F5GX36, Q86YH7, Q9UND6 |
| UniProt Entry Name | HDAC4_HUMAN |
| Gene Symbol | HDAC4 |
| GeneID | 9759 |
| NCBI Accession | NP_006028.2 |
| KEGG | hsa:9759 |
| String | 9606.ENSP00000264606 |
| Buffer | PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol. |
| Concentration | 1 mg/ml |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |