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Hepatitis B Surface Antigen (HBsAg) Antibody
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Catalogue No: abx240304
Price:
US$406.00
(Size: 100 µg)
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Hepatitis B Surface Antigen (HBsAg) Antibody is a Mouse Monoclonal antibody for the detection of HBsAg mouse. The large envelope protein exists in two topological conformations, one which is termed 'external' or Le-HBsAg and the other 'internal' or Li-HBsAg. In its external conformation the protein attaches the virus to cell receptors and thereby initiating infection. This interaction determines the species specificity and liver tropism. This attachment induces virion internalization predominantly through caveolin-mediated endocytosis. The large envelope protein also assumes fusion between virion membrane and endosomal membrane (Probable). In its internal conformation the protein plays a role in virion morphogenesis and mediates the contact with the nucleocapsid like a matrix protein.
Research Articles on Hepatitis B Surface Antigen (HBsAg)
| Target | Hepatitis B Surface Antigen (HBsAg) |
| Clonality | Monoclonal |
| Reactivity | Human |
| Tested Applications | ELISA, LF, CLIA |
| Host | Mouse |
| Recommended dilutions | Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | HBsAg |
| Isotype | IgG2a |
| Form | Liquid |
| Purity | ≥ 95% (SDS-PAGE) |
| Purification | Purified by Protein A and Protein G affinity chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Validity | 12 months. |
| Molecular Weight | Observed MW: 33 kDa |
| Buffer | PBS, pH 7.3, with 0.02% sodium azide and 50% glycerol. |
| Concentration | 2 mg/ml |
| Availability | Shipped within 5-12 working days. |
| Note | This product is for research use only. |