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Hepcidin (HAMP) Antibody
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Catalogue No: abx001348
Price:
US$203.00
(Size: 20 µl)
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HAMP Antibody is a Rabbit Polyclonal antibody against HAMP. The product encoded by this gene is involved in the maintenance of iron homeostasis, and it is necessary for the regulation of iron storage in macrophages, and for intestinal iron absorption. The preproprotein is post-translationally cleaved into mature peptides of 20, 22 and 25 amino acids, and these active peptides are rich in cysteines, which form intramolecular bonds that stabilize their beta-sheet structures. These peptides exhibit antimicrobial activity. Mutations in this gene cause hemochromatosis type 2B, also known as juvenile hemochromatosis, a disease caused by severe iron overload that results in cardiomyopathy, cirrhosis, and endocrine failure. [provided by RefSeq, Jul 2008].
Research Articles on Hepcidin (HAMP)
| Target | Hepcidin (HAMP) |
| Clonality | Polyclonal |
| Reactivity | Human, Mouse |
| Tested Applications | WB |
| Host | Rabbit |
| Recommended dilutions | WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 1-84 of human Hepcidin. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified by affinity chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | P81172 (UniProt, ExPASy) |
| UniProt Secondary AC | Q1HE14, Q9BY68 |
| UniProt Entry Name | HEPC_HUMAN |
| GeneID | 57817 |
| NCBI Accession | NP_066998.1 |
| KEGG | hsa:57817 |
| String | 9606.ENSP00000471894 |
| Molecular Weight | Calculated MW: 9 kDa Observed MW: 10 kDa |
| Buffer | PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol. |
| Concentration | > 0.2 mg/ml |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |