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Homocysteine Inducible Endoplasmic Reticulum Stress Inducible Ubiquitin Like Domain Member 1 (HERPUD1) Antibody
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Catalogue No: abx029371
Price:
US$290.00
(Size: 80 µl)
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The accumulation of unfolded proteins in the endoplasmic reticulum (ER) triggers the ER stress response. This response includes the inhibition of translation to prevent further accumulation of unfolded proteins, the increased expression of proteins involved in polypeptide folding, known as the unfolded protein response (UPR), and the destruction of misfolded proteins by the ER-associated protein degradation (ERAD) system. This gene may play a role in both UPR and ERAD. Its expression is induced by UPR and it has an ER stress response element in its promoter region while the encoded protein has an N-terminal ubiquitin-like domain which may interact with the ERAD system. This protein has been shown to interact with presenilin proteins and to increase the level of amyloid-beta protein following its overexpression. Alternative splicing of this gene produces multiple transcript variants, some encoding different isoforms. The full-length nature of all transcript variants has not been determined. [provided by RefSeq].
Research Articles on Homocysteine Inducible Endoplasmic Reticulum Stress Inducible Ubiquitin Like Domain Member 1 (HERPUD1)
| Target | Homocysteine Inducible Endoplasmic Reticulum Stress Inducible Ubiquitin Like Domain Member 1 (HERPUD1) |
| Clonality | Polyclonal |
| Reactivity | Human |
| Tested Applications | ELISA, WB |
| Host | Rabbit |
| Recommended dilutions | WB: 1/1000. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | KLH-conjugated synthetic peptide between 55-83 amino acids from the N-terminal region of human HERPUD1. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified through a protein A column, followed by peptide affinity purification. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | Q15011 (UniProt, ExPASy) |
| UniProt Secondary AC | E9PGD1, O60644, Q6IAN8, Q96D92 |
| UniProt Entry Name | HERP1_HUMAN |
| KEGG | hsa:9709 |
| String | 9606.ENSP00000409555 |
| Molecular Weight | Calculated MW: 43.7 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |