Histone H2B Type 1-C/E/F/G/I (HIST1H2BG) Antibody

Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene is intronless and encodes a member of the histone H2B family. Transcripts from this gene lack polyA tails but instead contain a palindromic termination element. This gene is found in the large histone gene cluster on chromosome 6. [provided by RefSeq].

Target	Histone H2B Type 1-C/E/F/G/I (HIST1H2BG)
Clonality	Polyclonal
Reactivity	Human, Zebrafish
Tested Applications	ELISA, WB
Host	Rabbit
Recommended dilutions	WB: 1/500. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	KLH-conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human HIST1H2BG.
Isotype	IgG
Form	Liquid
Purification	Purified through a protein A column, followed by peptide affinity purification.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	P62807 (UniProt, ExPASy)
UniProt Secondary AC	P02278, Q3B872, Q4VB69, Q93078, Q93080
UniProt Entry Name	H2B1C_HUMAN
KEGG	hsa:3017 hsa:8339 hsa:8343 hsa:8344 hsa:8346 hsa:8347
String	9606.ENSP00000483237
Molecular Weight	Calculated MW: 13.9 kDa
Buffer	PBS containing 0.09% sodium azide.
Specificity	Predicted to react with Mouse, Cow, Monkey and Xenopus H2BC4.
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Histone H2B Type 1-C/E/F/G/I (HIST1H2BG)

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