Histone Deacetylase 4 (HDAC4) Antibody

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Catalogue No: abx010899
Price: US$406.00
(Size: 100 µg)
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WB analysis of HeLa cells, using HDAC4 antibody (1/1000 dilution).
Histone Deacetylase 4 (HDAC4) Antibody

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Histone Deacetylase 4 (HDAC4) Antibody is a Rabbit Polyclonal antibody for the detection of HDAC4.

Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to class II of the histone deacetylase/acuc/apha family. It possesses histone deacetylase activity and represses transcription when tethered to a promoter. This protein does not bind DNA directly, but through transcription factors MEF2C and MEF2D. It seems to interact in a multiprotein complex with RbAp48 and HDAC3.

Target Histone Deacetylase 4 (HDAC4)
Clonality Polyclonal
Reactivity Human, Mouse
Tested Applications ELISA, WB
Host Rabbit
Recommended dilutions WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user.
Conjugation Unconjugated
Immunogen histone deacetylase 4
Isotype IgG
Form Liquid
Purity ≥ 95% (SDS-PAGE)
Purification Purified by immunogen affinity chromatography.
Storage Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
Validity 12 months.
UniProt Primary AC P56524 (UniProt, ExPASy)
UniProt Secondary AC E9PGB9, F5GX36, Q86YH7, Q9UND6
UniProt Entry Name HDAC4_HUMAN
Gene Symbol HDAC4
GeneID 9759
OMIM 600430
HGNC 14063
KEGG hsa:9759
Ensembl ENSG00000068024
String 9606.ENSP00000264606
Molecular Weight Observed MW: 130 kDa
Buffer PBS, pH 7.3, with 0.02% sodium azide and 50% glycerol.
Concentration 2 mg/ml
Availability Shipped within 5-12 working days.
Note THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION.
Research Articles on Histone Deacetylase 4 (HDAC4)
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