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Histone H3 (H3) Antibody
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Catalogue No: abx025760
Price:
US$326.25
(Size: 80 µl)
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Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. The protein targeted by this antibody is a replication-independent member of the histone H3 family.
Research Articles on Histone H3 (H3)
| Target | Histone H3 (H3) |
| Clonality | Polyclonal |
| Reactivity | Human |
| Tested Applications | ELISA, WB |
| Host | Rabbit |
| Recommended dilutions | WB: 1/1000. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | KLH-conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human Histone H3. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | P84243 (UniProt, ExPASy) |
| UniProt Secondary AC | P06351, P33155, Q5VV55, Q5VV56, Q66I33, Q9V3W4 |
| UniProt Entry Name | H33_HUMAN |
| KEGG | hsa:3020 hsa:3021 |
| String | 9606.ENSP00000355778 |
| Molecular Weight | Calculated MW: 15.3 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Specificity | Predicted to react with Mouse, Rat, Cow, Pig, Chicken, Yeast, Zebrafish, Drosophila, Xenopus and C. elegans H3-3A. |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |