Histone-Lysine N-Methyltransferase EZH2 (EZH2) Antibody

EZH2 Antibody is a Rabbit Polyclonal antibody against EZH2. This gene encodes a member of the Polycomb-group (PcG) family. PcG family members form multimeric protein complexes, which are involved in maintaining the transcriptional repressive state of genes over successive cell generations. This protein associates with the embryonic ectoderm development protein, the VAV1 oncoprotein, and the X-linked nuclear protein. This protein may play a role in the hematopoietic and central nervous systems. Multiple alternatively splcied transcript variants encoding distinct isoforms have been identified for this gene.

Target	Histone-Lysine N-Methyltransferase EZH2 (EZH2)
Clonality	Polyclonal
Reactivity	Human, Mouse, Rat
Tested Applications	WB, IHC, IP
Host	Rabbit
Recommended dilutions	WB: 1/500 - 1/1000, IHC-P: 1/50 - 1/200, IP: 0.5-4 µg/200-400 µg whole cell extracts. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	Recombinant fusion protein containing a sequence corresponding to amino acids 133-252 of human EZH2/KMT6.
Isotype	IgG
Form	Liquid
Purification	Purified by affinity chromatography.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	Q15910 (UniProt, ExPASy)
UniProt Entry Name	EZH2_HUMAN
Gene Symbol	EZH2
GeneID	2146
NCBI Accession	NP_001190176.1
KEGG	hsa:2146
String	9606.ENSP00000320147
Molecular Weight	Calculated MW: 85 kDa Observed MW: 98 kDa
Buffer	PBS, pH 7.3, containing 0.05% Proclin-300, 50% glycerol.
Concentration	> 0.2 mg/ml
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Histone-Lysine N-Methyltransferase EZH2 (EZH2)

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