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Histone-Lysine N-Methyltransferase EZH2 (EZH2) Antibody
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Catalogue No: abx004393
Price:
US$217.50
(Size: 20 µl)
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EZH2 Antibody is a Rabbit Polyclonal antibody against EZH2. This gene encodes a member of the Polycomb-group (PcG) family. PcG family members form multimeric protein complexes, which are involved in maintaining the transcriptional repressive state of genes over successive cell generations. This protein associates with the embryonic ectoderm development protein, the VAV1 oncoprotein, and the X-linked nuclear protein. This protein may play a role in the hematopoietic and central nervous systems. Multiple alternatively splcied transcript variants encoding distinct isoforms have been identified for this gene.
Research Articles on Histone-Lysine N-Methyltransferase EZH2 (EZH2)
| Target | Histone-Lysine N-Methyltransferase EZH2 (EZH2) |
| Clonality | Polyclonal |
| Reactivity | Human, Mouse, Rat |
| Tested Applications | ELISA, WB, IHC, IP |
| Host | Rabbit |
| Recommended dilutions | ELISA: 1 µg/ml, WB: 1/500 - 1/1000, IHC-P: 1/50 - 1/200, IP: 0.5 µg - 4 µg antibody per 200 µg - 400 µg extracts of whole cells. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 133-252 of human EZH2/KMT6. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified by affinity chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | Q15910 (UniProt, ExPASy) |
| UniProt Entry Name | EZH2_HUMAN |
| Gene Symbol | EZH2 |
| GeneID | 2146 |
| NCBI Accession | NP_001190176.1 |
| KEGG | hsa:2146 |
| String | 9606.ENSP00000320147 |
| Molecular Weight | Calculated MW: 85 kDa Observed MW: 98 kDa |
| Buffer | PBS, pH 7.3, containing 0.05% Proclin-300, 50% glycerol. |
| Concentration | > 0.2 mg/ml |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |