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Hexokinase 1 (HK1) Antibody
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Catalogue No: abx000977
Price:
US$232.00
(Size: 20 µl)
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HK1 Antibody is a Rabbit Polyclonal antibody against HK1. Hexokinases phosphorylate glucose to produce glucose-6-phosphate, the first step in most glucose metabolism pathways. This gene encodes a ubiquitous form of hexokinase which localizes to the outer membrane of mitochondria. Mutations in this gene have been associated with hemolytic anemia due to hexokinase deficiency. Alternative splicing of this gene results in five transcript variants which encode different isoforms, some of which are tissue-specific. Each isoform has a distinct N-terminus; the remainder of the protein is identical among all the isoforms. A sixth transcript variant has been described, but due to the presence of several stop codons, it is not thought to encode a protein.
Research Articles on Hexokinase 1 (HK1)
| Target | Hexokinase 1 (HK1) |
| Clonality | Polyclonal |
| Reactivity | Human, Mouse, Rat |
| Tested Applications | WB, IHC, IF/ICC, IP |
| Host | Rabbit |
| Recommended dilutions | WB: 1/500 - 1/1000, IHC-P: 1/50 - 1/200, IF/ICC: 1/50 - 1/200, IP: 0.5-4 µg/200-400 µg whole cell extracts. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 21-219 of human HK1. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified by affinity chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | P19367 (UniProt, ExPASy) |
| UniProt Entry Name | HXK1_HUMAN |
| Gene Symbol | HK1 |
| GeneID | 3098 |
| NCBI Accession | NP_000179.2 |
| KEGG | hsa:3098 |
| String | 9606.ENSP00000402103 |
| Molecular Weight | Calculated MW: 102 kDa Observed MW: 102 kDa |
| Buffer | PBS, pH 7.3, containing 0.01% thimerosal, 50% glycerol. |
| Concentration | 1.21 mg/ml |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |