HLA Class II Histocompatibility Antigen, DQ Alpha 2 Chain (HLA-DQA2) Antibody

This gene belongs to the HLA class II alpha chain family. The encoded protein forms a heterodimer with a class II beta chain. It is located in intracellular vesicles and plays a central role in the peptide loading of MHC class II molecules by helping to release the CLIP molecule from the peptide binding site. Class II molecules are expressed in antigen presenting cells (B lymphocytes, dendritic cells, macrophages) and are used to present antigenic peptides on the cell surface to be recognized by CD4 T-cells. [provided by RefSeq].

Target	HLA Class II Histocompatibility Antigen, DQ Alpha 2 Chain (HLA-DQA2)
Clonality	Polyclonal
Reactivity	Human
Tested Applications	ELISA, WB
Host	Rabbit
Recommended dilutions	WB: 1/1000. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	KLH-conjugated synthetic peptide between 39-66 amino acids from the Central region of human HLA-DQA2.
Isotype	IgG
Form	Liquid
Purification	Purified through a protein A column, followed by peptide affinity purification.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	P01906 (UniProt, ExPASy)
UniProt Secondary AC	A2BF37, B0V0E7, O19789, Q5SQ94, Q5SR04
UniProt Entry Name	DQA2_HUMAN
Gene Symbol	HLA-DQA2
GeneID	3118
OMIM	613503
NCBI Accession	NP_064440.1
HGNC	4943
KEGG	hsa:3118
Ensembl	ENSG00000206301
String	9606.ENSP00000364076
Molecular Weight	Calculated MW: 28 kDa
Buffer	PBS containing 0.09% sodium azide.
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on HLA Class II Histocompatibility Antigen, DQ Alpha 2 Chain (HLA-DQA2)

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