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Major Histocompatibility Complex Class I E (HLA-E/MHCE) Antibody
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Catalogue No: abx139495
Price:
US$391.50
(Size: 0.1 mg)
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HLA-E Antibody is a Mouse Monoclonal against HLA-E.
Research Articles on Major Histocompatibility Complex Class I E (HLA-E/MHCE)
| Target | Major Histocompatibility Complex Class I E (HLA-E/MHCE) |
| Clonality | Monoclonal |
| Clone | W249 |
| Reactivity | Human, Monkey |
| Tested Applications | IHC, FCM, IP |
| Host | Mouse |
| Recommended dilutions | Validated in IHC-P. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Bacterially expressed recombinant HLA-E refolded with beta2-microglobulin and peptide. |
| Isotype | IgG1 |
| Purity | > 95% (SDS-PAGE) |
| Purification | Purified by Protein A affinity chromatography. |
| Storage | Store at 2-8°C. Do not freeze. |
| UniProt Primary AC | P13747 (UniProt, ExPASy) |
| Gene Symbol | HLA-E |
| GeneID | 3133 |
| KEGG | hsa:3133 |
| String | 9606.ENSP00000365817 |
| Buffer | PBS solution with 15 mM sodium azide. |
| Specificity | The antibody recognized native surface-expressed HLA-E, but not denaturated heavy chain of HLA-E. HLA-E belongs to the MHC Class I molecules (MHC Class Ib; nonclassical) and it is expressed on many types of the human cells. The published results showed that the antibody cross-reacts with some classical MHC Class I molecules (HLA-A3, -A11, -B7). However, the recent Workshop I Session on the 3rd International Conference on HLA-G (Paris, July 2003) confirmed that the antibody exhibits much broader cross-reactivity classical MHC Class I antigens, namely with HLA-A24, -A32, -B8, -B15, -B27, -B35, -B44, -B54, -C3, -C4, -C5, -C7. |
| Concentration | 1 mg/ml |
| Availability | Shipped within 5-12 working days. |
| Note | This product is for research use only. |