High Mobility Group Protein HMGI-C (HMGA2) Antibody

This gene encodes a protein that belongs to the non-histone chromosomal high mobility group (HMG) protein family. HMG proteins function as architectural factors and are essential components of the enhancesome. This protein contains structural DNA-binding domains and may act as a transcriptional regulating factor. Identification of the deletion, amplification, and rearrangement of this gene that are associated with myxoid liposarcoma suggests a role in adipogenesis and mesenchymal differentiation. A gene knock out study of the mouse counterpart demonstrated that this gene is involved in diet-induced obesity. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. This antibody is supplied as crude ascites.

Target	High Mobility Group Protein HMGI-C (HMGA2)
Clonality	Monoclonal
Reactivity	Human
Tested Applications	ELISA, WB
Host	Mouse
Recommended dilutions	WB: 1/500 - 1/8000. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	KLH-conjugated synthetic peptide between 64-92 amino acids from human HMG2.
Isotype	IgG2b
Form	Liquid
Purification	Unpurified crude ascites.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	P52926 (UniProt, ExPASy)
UniProt Secondary AC	E7EP85, E7EWA2, Q1M182, Q1M185, Q1M186, Q1M187, Q1M188
UniProt Entry Name	HMGA2_HUMAN
KEGG	hsa:8091
String	9606.ENSP00000437621
Molecular Weight	Calculated MW: 11.8 kDa
Buffer	Ascites containing 0.09% sodium azide.
Specificity	Predicted to react with Mouse HMGA2.
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on High Mobility Group Protein HMGI-C (HMGA2)

Write a review

Your Name

Your Email Address

PMID

DOI

Your Review

Rating

Continue