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High Mobility Group Protein HMGI-C (HMGA2) Antibody
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Catalogue No: abx032494
Price:
US$326.25
(Size: 80 µl)
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This gene encodes a protein that belongs to the non-histone chromosomal high mobility group (HMG) protein family. HMG proteins function as architectural factors and are essential components of the enhancesome. This protein contains structural DNA-binding domains and may act as a transcriptional regulating factor. Identification of the deletion, amplification, and rearrangement of this gene that are associated with myxoid liposarcoma suggests a role in adipogenesis and mesenchymal differentiation. A gene knock out study of the mouse counterpart demonstrated that this gene is involved in diet-induced obesity. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
Research Articles on High Mobility Group Protein HMGI-C (HMGA2)
| Target | High Mobility Group Protein HMGI-C (HMGA2) |
| Clonality | Polyclonal |
| Reactivity | Human |
| Tested Applications | ELISA, WB, FCM |
| Host | Rabbit |
| Recommended dilutions | WB: 1/1000, FCM: 1/10 - 1/50. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | KLH-conjugated synthetic peptide between 64-92 amino acids from the C-terminal region of human HMGA2. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified through a protein A column, followed by peptide affinity purification. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | P52926 (UniProt, ExPASy) |
| UniProt Secondary AC | E7EP85, E7EWA2, Q1M182, Q1M185, Q1M186, Q1M187, Q1M188 |
| UniProt Entry Name | HMGA2_HUMAN |
| NCBI Accession | NP_003474.1 NP_003475.1 |
| KEGG | hsa:8091 |
| String | 9606.ENSP00000437621 |
| Molecular Weight | Calculated MW: 11.8 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Specificity | Predicted to react with Mouse HMGA2. |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |