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High Mobility Group Protein HMGI-C (HMGA2) Antibody
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Catalogue No: abx002163
Price:
US$203.00
(Size: 20 µl)
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HMGA2 Antibody is a Rabbit Polyclonal antibody against HMGA2. This gene encodes a protein that belongs to the non-histone chromosomal high mobility group (HMG) protein family. HMG proteins function as architectural factors and are essential components of the enhancesome. This protein contains structural DNA-binding domains and may act as a transcriptional regulating factor. Identification of the deletion, amplification, and rearrangement of this gene that are associated with myxoid liposarcoma suggests a role in adipogenesis and mesenchymal differentiation. A gene knock out study of the mouse counterpart demonstrated that this gene is involved in diet-induced obesity. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
Research Articles on High Mobility Group Protein HMGI-C (HMGA2)
| Target | High Mobility Group Protein HMGI-C (HMGA2) |
| Clonality | Polyclonal |
| Reactivity | Human, Mouse, Rat |
| Tested Applications | WB, IHC |
| Host | Rabbit |
| Recommended dilutions | WB: 1/500 - 1/1000, IHC-P: 1/50 - 1/200. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 55-109 of human HMGA2. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified by affinity chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | P52926 (UniProt, ExPASy) |
| UniProt Secondary AC | E7EP85, E7EWA2, Q1M182, Q1M185, Q1M186, Q1M187, Q1M188 |
| UniProt Entry Name | HMGA2_HUMAN |
| Gene Symbol | HMGA2 |
| GeneID | 8091 |
| NCBI Accession | NP_003474.1 |
| KEGG | hsa:8091 |
| String | 9606.ENSP00000437621 |
| Molecular Weight | Calculated MW: 12 kDa Observed MW: 18 kDa |
| Buffer | PBS, pH 7.3, containing 0.05% Proclin-300, 50% glycerol. |
| Concentration | > 0.2 mg/ml |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |