High Mobility Group Nucleosome-Binding Domain-Containing Protein 3 (HMGN3) Antibody

Thyroid hormone receptors are hormone-dependent transcription factors that regulate expression of a variety of specific target genes. The protein encoded by this gene binds thyroid hormone receptor beta, but only in the presence of thyroid hormone. The encoded protein, a member of the HMGN protein family, is thought to reduce the compactness of the chromatin fiber in nucleosomes, thereby enhancing transcription from chromatin templates. Two transcript variants encoding different isoforms have been found for this gene.

Target	High Mobility Group Nucleosome-Binding Domain-Containing Protein 3 (HMGN3)
Clonality	Polyclonal
Reactivity	Human
Tested Applications	ELISA, WB
Host	Rabbit
Recommended dilutions	WB: 1/1000. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	KLH-conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human HMGN3.
Isotype	IgG
Form	Liquid
Purification	Purified through a protein A column, followed by peptide affinity purification.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	Q15651 (UniProt, ExPASy)
UniProt Secondary AC	B2RD37, Q5HYD3, Q7RTT0, Q969M5, Q9BZT7
UniProt Entry Name	HMGN3_HUMAN
KEGG	hsa:9324
Molecular Weight	Calculated MW: 10.7 kDa
Buffer	PBS containing 0.09% sodium azide.
Specificity	Predicted to react with Mouse and Cow HMGN3.
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on High Mobility Group Nucleosome-Binding Domain-Containing Protein 3 (HMGN3)

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