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Hepatocyte Nuclear Factor 1-Beta (HNF1B) Antibody
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Catalogue No: abx026093
Price:
US$290.00
(Size: 80 µl)
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This gene encodes a member of the homeodomain-containing superfamily of transcription factors. The protein binds to DNA as either a homodimer, or a heterodimer with the related protein hepatocyte nuclear factor 1-alpha. The gene has been shown to function in nephron development, and regulates development of the embryonic pancreas. Mutations in this gene result in renal cysts and diabetes syndrome and noninsulin-dependent diabetes mellitus, and expression of this gene is altered in some types of cancer. Multiple transcript variants encoding different isoforms have been found for this gene.
Research Articles on Hepatocyte Nuclear Factor 1-Beta (HNF1B)
| Target | Hepatocyte Nuclear Factor 1-Beta (HNF1B) |
| Clonality | Polyclonal |
| Reactivity | Human |
| Tested Applications | ELISA, WB |
| Host | Rabbit |
| Recommended dilutions | WB: 1/1000. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | KLH-conjugated synthetic peptide between 498-529 amino acids from the C-terminal region of human HNF1B. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified through a protein A column, followed by peptide affinity purification. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | P35680 (UniProt, ExPASy) |
| UniProt Secondary AC | B4DKM3, E0YMJ9 |
| UniProt Entry Name | HNF1B_HUMAN |
| Gene Symbol | HNF1B |
| KEGG | hsa:6928 |
| String | 9606.ENSP00000480291 |
| Molecular Weight | Calculated MW: 61.3 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Specificity | Predicted to react with Mouse and Rat HNF1B. |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |