Hepatocyte Nuclear Factor 1-Beta (HNF1B) Antibody

This gene encodes a member of the homeodomain-containing superfamily of transcription factors. The protein binds to DNA as either a homodimer, or a heterodimer with the related protein hepatocyte nuclear factor 1-alpha. The gene has been shown to function in nephron development, and regulates development of the embryonic pancreas. Mutations in this gene result in renal cysts and diabetes syndrome and noninsulin-dependent diabetes mellitus, and expression of this gene is altered in some types of cancer. Multiple transcript variants encoding different isoforms have been found for this gene.

Target	Hepatocyte Nuclear Factor 1-Beta (HNF1B)
Clonality	Polyclonal
Reactivity	Human
Tested Applications	ELISA, WB
Host	Rabbit
Recommended dilutions	WB: 1/1000. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	KLH-conjugated synthetic peptide between 498-529 amino acids from the C-terminal region of human HNF1B.
Isotype	IgG
Form	Liquid
Purification	Purified through a protein A column, followed by peptide affinity purification.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	P35680 (UniProt, ExPASy)
UniProt Secondary AC	B4DKM3, E0YMJ9
UniProt Entry Name	HNF1B_HUMAN
Gene Symbol	HNF1B
KEGG	hsa:6928
String	9606.ENSP00000480291
Molecular Weight	Calculated MW: 61.3 kDa
Buffer	PBS containing 0.09% sodium azide.
Specificity	Predicted to react with Mouse and Rat HNF1B.
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Hepatocyte Nuclear Factor 1-Beta (HNF1B)

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