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Histamine N-Methyltransferase (HNMT) Antibody
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Catalogue No: abx025394
Price:
US$326.25
(Size: 80 µl)
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In mammals, histamine is metabolized by two major pathways: N (tau) methylation via histamine N-methyltransferase and oxidative deamination via diamine oxidase. This gene encodes the first enzyme which is found in the cytosol and uses S-adenosyl-L-methionine as the methyl donor. In the mammalian brain, the neurotransmitter activity of histamine is controlled by N (tau) methylation as diamine oxidase is not found in the central nervous system. A common genetic polymorphism affects the activity levels of this gene product in red blood cells. Multiple alternatively spliced transcript variants that encode different proteins have been found for this gene.
Research Articles on Histamine N-Methyltransferase (HNMT)
| Target | Histamine N-Methyltransferase (HNMT) |
| Clonality | Monoclonal |
| Reactivity | Human |
| Tested Applications | ELISA, WB |
| Host | Mouse |
| Recommended dilutions | WB: 1/100 - 1/1000. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Purified His-tagged Human HNMT protein (Fragment) |
| Isotype | IgG1 |
| Form | Liquid |
| Purification | Purified Mouse Monoclonal Antibody. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | P50135 (UniProt, ExPASy) |
| UniProt Secondary AC | B2R9J3, Q546Z6, Q7Z7I2, Q8IU56, Q8WW98, Q9BRW6 |
| UniProt Entry Name | HNMT_HUMAN |
| KEGG | hsa:3176 |
| String | 9606.ENSP00000280097 |
| Molecular Weight | Calculated MW: 33.3 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |