Heterogeneous Nuclear Ribonucleoprotein C1/C2 (HNRNPC) Antibody

This gene belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are RNA binding proteins and they complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene can act as a tetramer and is involved in the assembly of 40S hnRNP particles. Multiple transcript variants encoding at least two different isoforms have been described for this gene. [provided by RefSeq].

Target	Heterogeneous Nuclear Ribonucleoprotein C1/C2 (HNRNPC)
Clonality	Polyclonal
Reactivity	Human
Tested Applications	ELISA, WB, IHC
Host	Rabbit
Recommended dilutions	WB: 1/1000, IHC-P: 1/50 - 1/100. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	KLH-conjugated synthetic peptide between 279-306 amino acids from the C-terminal region of human HNRNPC.
Isotype	IgG
Form	Liquid
Purification	Purified through a protein A column, followed by peptide affinity purification.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	P07910 (UniProt, ExPASy)
UniProt Entry Name	HNRPC_HUMAN
KEGG	hsa:3183
String	9606.ENSP00000451291
Molecular Weight	Calculated MW: 33.7 kDa
Buffer	PBS containing 0.09% sodium azide.
Specificity	Predicted to react with Mouse, Rat and Rabbit HNRNPC.
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Heterogeneous Nuclear Ribonucleoprotein C1/C2 (HNRNPC)

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